The Biosafety Concerned Metal Oxide Nanoparticles: Catalytic Activity Test

조회수 : 17 등록일 : 2018.09.12 15:41

일시 : 2018.09.12 17:00
소속 : 숙명여자대학교 화학과
발표자 : 이한길
장소 : AS510

Despite advances in the construction of catalysts based on metal oxide nanoparticles (MO NPs) for various biochemical and biomedical applications, the biosafety concerns about these NPs still remain. Recently, the need to analyze and improve the safety of MO NPs along with attempts to enhance their catalytic performance has been strongly perceived. Here, we first prepared multiple variants of transition metal doped metal oxide (TM@MO) NPs under different pH conditions; then, we assessed their toxicity and finally screened the best catalytic performance. To assess the NP toxicity, the NPs were introduced into three different types of human cells to be most affected by NPs (skin, lung, and kidney) because these parts would be mainly in contact with materials from the outer environment. This demonstrates that TM@MO NPs with enhanced activities and insignificant toxicity can be effectively developed and further suggests a potential for the use of these NPs in conventional chemical reactions as well as in emerged biomedical applications.

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