Unconventional Biosensor : Advanced Biocompatible Sensing Systems

조회수 : 413 등록일 : 2016.06.15 08:52

일시 : 2016.06.15 17:00
소속 : Department of Materials Science and Engineering
발표자 : 고아현
장소 : R404
Sensors in biomedical applications monitoring critical chemical information (e.g.,
pH and glucose) and physical vital signs (e.g., Temperature and ECG) are utilized with
rigid electrodes and thus, limit intimate integration with our bodies that are soft, curved,
stretched, and continuously evolving. The mismatch of mechanical properties between
sensors and dynamic living biological systems causes tissue damage and/or induce the
foreign body response, leading to inaccurate measurements. Additionally, unconformable
contact of sensors on body system impedes their function of the device in biomedical and
wearable health monitoring application. Therefore, my research has been focused on
developing biosensors to enable quantitative analytical detection along with enhancing
the biocompatibility of mechanical and chemical properties of devices. These
unconventional biosensors hold great potential to improve human life and health indeed.
Herein, I will present the development of biocompatible biosensors: (1) nitric oxidereleasing
implantable electrochemical glucose sensor for mitigating the foreign body
response; (2) ultrathin injectable temperature sensors for cardiac ablation monitoring; and
(3) epidermal microfluidic sensor with wireless communication electronics for sweat
monitoring. Each sensor was specifically developed to eliminate profound mismatch in
mechanical properties or to mimic active biological system exploiting the role of a living
system. These unique approaches in developing biomedical sensors—skin-mounted,
flexible, and/or active continuous drug-releasing sensor membrane—bring significant
advances in biomedical and mobile health applications.
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