Publication

Synthesis of pyrrolo[2,1-f][1,2,4]triazin-4(3H)-ones: Rearrangement of pyrrolo[1,2-d][1,3,4]oxadiazines and regioselective intramolecular cyclization of 1,2-biscarbamoyl-substituted 1H-pyrroles

조회수 : 151 등록일 : 2016.10.03 00:00

저자 : Son, K (Son, Kkonnip)
출처 : BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY
출판일 : 2016.08.09
 
 
Synthesis of pyrrolo[2,1-f][1,2,4]triazin-4(3H)-ones: Rearrangement of pyrrolo[1,2-d][1,3,4]oxadiazines and regioselective intramolecular cyclization of 1,2-biscarbamoyl-substituted 1H-pyrroles
 
 
Son, K (Son, Kkonnip)[ 1,2 ] ; Park, SJ (Park, Seong Jun)[ 1 ]
 
 
[ 1 ] KRICT, Res Ctr Med Chem, 141 Gajeong Ro, Daejeon 305600, South Korea
[ 2 ] Sogang Univ, Dept Chem, 35 Baekbeom Ro, Seoul 121742, South Korea
 
 
 
Pyrrolo[2,1-f][1,2,4]triazin-4(3H)-ones 12 have been easily prepared via nucleophile-induced rearrangement of pyrrolooxadiazines 11 and regioselective intramolecular cyclization of 1,2-biscarbamoyl-substituted 1H-pyrroles 10. In this work, we demonstrated that the described synthetic approaches can be considered to be more facile and practical than previously reported procedures.
 
 
 
 
 

 
  • 목록보기
  • 이전글보기
  • 다음글보기